New study finds drug cocktail reduces ageing-associated disc degeneration

One of the major contributors to low back pain is the degeneration of the discs that cushion and support vertebrae.

A study conducted by researchers found that the treatment with a drug cocktail removes ageing cells and also reduces disc degeneration.

 

One of the major contributors to low back pain is the degeneration of the discs that cushion and support vertebrae. It is a common occurrence of ageing.

 

The Researchers at Thomas Jefferson University found out two senolytic drugs called the dasatinib and quercetin. If it is taken as injections in a young age, it mitigated disc generation in old age.

 

Makarand Risbud, a Professor of the Spine Research in orthopaedic surgery said "Once intervertebral discs start to degenerate, there is very little regeneration that happens.

 

But our results show that it is possible to mitigate the disc degeneration that happens with ageing".

 

Presently, surgery or steroid injections help treat low back pain from disc degeneration but majority of the patients do not fulfill the criteria for surgery. It is also noted that using strong painkillers for a long time can carry the risk of addiction. The new findings are shown in the journal Nature Communications.

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